Osteogenic and Biocompatibility Potential of Polylactic Acid-Based Materials: A Systematic Review of Human Primary Cells Studies

Native polylactic acid-based materials display limited bioactivity. However, functionalization through bioceramics incorporation, growth factor delivery, and surface topographical modification is crucial for transforming them into bioactive scaffolds capable of achieving the dual biofunctionality required for successful GBR.

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Publication Details

Journal
Journal of Functional Biomaterials
Published
2026-01-09
DOI
https://doi.org/10.3390/jfb17010034
Primary Topic
Bone Tissue Engineering Materials
Type
article
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article

Osteogenic and Biocompatibility Potential of Polylactic Acid-Based Materials: A Systematic Review of Human Primary Cells Studies

Emilio Alfredo Cafferata, Mario Guerrero-Torres, Silvia M. Becerra-Bayona, Martha L. Arango-Rodríguez
Journal of Functional Biomaterials
Bone Tissue Engineering Materials
article

Osteogenic and Biocompatibility Potential of Polylactic Acid-Based Materials: A Systematic Review of Human Primary Cells Studies

Emilio Alfredo Cafferata, Mario Guerrero-Torres, Silvia M. Becerra-Bayona, Martha L. Arango-Rodríguez
article en

Abstract

Native polylactic acid-based materials display limited bioactivity. However, functionalization through bioceramics incorporation, growth factor delivery, and surface topographical modification is crucial for transforming them into bioactive scaffolds capable of achieving the dual biofunctionality required for successful GBR.

Journal of Functional BiomaterialsVol. 17(1)
Universidad Autónoma de Bucaramanga (CO), Universidad Científica del Sur (PE), Universidad Santo Tomás (CO), Foscal Hospital (CO)
Openalex Percentile: Top 94%
Bone Tissue Engineering Materials
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