Artichoke Extract Ameliorates CCl4-Induced Hepatocellular Carcinoma in AlbinoRats by Regulating the Phosphatidylinositol 3-kinase/serine-threonine ProteinKinase Pathway

We conclude that the up-regulation of the Caspase 3 and Caspase 9 pathways and the suppression of PI3K/AKT signalling pathways may be the mechanisms behind the anti-tumor actions of artichoke extract.

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Publication Details

Journal
Anti-Cancer Agents in Medicinal Chemistry
Published
2026-01-07
DOI
https://doi.org/10.2174/0118715206397860251023042637
Primary Topic
Cynara cardunculus studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Artichoke Extract Ameliorates CCl4-Induced Hepatocellular Carcinoma in AlbinoRats by Regulating the Phosphatidylinositol 3-kinase/serine-threonine ProteinKinase Pathway

Nabila Gita Fitriana Zein, Eman Talaat, Maha M. Rashad, Fathy Yassin
Anti-Cancer Agents in Medicinal Chemistry
Cynara cardunculus studies
article

Artichoke Extract Ameliorates CCl4-Induced Hepatocellular Carcinoma in AlbinoRats by Regulating the Phosphatidylinositol 3-kinase/serine-threonine ProteinKinase Pathway

Nabila Gita Fitriana Zein, Eman Talaat, Maha M. Rashad, Fathy Yassin
article en

Abstract

We conclude that the up-regulation of the Caspase 3 and Caspase 9 pathways and the suppression of PI3K/AKT signalling pathways may be the mechanisms behind the anti-tumor actions of artichoke extract.

Anti-Cancer Agents in Medicinal ChemistryVol. 26
Cairo University (EG), Zagazig University (EG)
Openalex Percentile: Top 93%
Cynara cardunculus studies
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