<i> <b>Akkermansia muciniphila</b> </i> <b>modulates intestinal mucus composition to counteract high-fat diet-induced obesity in mice</b>
These findings highlight the protective effects of live <i>A. muciniphila</i> Muc<sup>T</sup> against diet-induced metabolic dysfunctions by modulating adiposity, mucus layer composition, and glycan profiles. This reinforces its potential as a therapeutic strategy for metabolic disorders associated with gut microbiota alterations.
Authors
- Nathalie M. Delzenne (ORCID: https://orcid.org/0000-0003-2115-6082)
- Matthias Van Hul (ORCID: https://orcid.org/0000-0002-5503-107X)
- Anthony Puel
- Patrice D. Cani (ORCID: https://orcid.org/0000-0003-2040-2448)
- Camille Petitfils (ORCID: https://orcid.org/0000-0002-6884-300X)
- Paola Paone (ORCID: https://orcid.org/0009-0000-9385-9890)
- Willem M. de Vos
- Nathalie Juge
- Dimitris Latousakis
Institutions
- University of Helsinki (FI)
- Quadram Institute (GB)
- Walloon Excellence in Lifesciences and Biotechnology (BE)
- Imperial College London (GB)
- Wageningen University & Research (NL)
- UCLouvain (BE)
Publication Details
- Journal
- Gut Microbes
- Published
- 2026-01-09
- DOI
- https://doi.org/10.1080/19490976.2025.2612580
- Citations
- 1
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 22.24