Association between GRIm score and response to nivolumab monotherapy in patients with advanced malignant melanoma

This study is the first to validate the GRIm Score in malignant melanoma, suggesting it is a valuable biomarker for patient selection in immunotherapy trials. The findings highlight its potential in refining treatment decisions, though further validation in larger, multicenter cohorts is required.

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Publication Details

Journal
Journal of Cancer Research and Clinical Oncology
Published
2026-01-08
DOI
https://doi.org/10.1007/s00432-025-06411-7
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
0.00
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article

Association between GRIm score and response to nivolumab monotherapy in patients with advanced malignant melanoma

Assoc, Heves Sürmeli, Uğur Özkerim, seval ay et al.
Journal of Cancer Research and Clinical Oncology
Cancer Immunotherapy and Biomarkers
article

Association between GRIm score and response to nivolumab monotherapy in patients with advanced malignant melanoma

Assoc, Heves Sürmeli, Uğur Özkerim, seval ay, Sila OKSUZ, Oguzcan Kinikoglu, Hatice Odabaş, Deniz Isik, Utku Donem Gundogdu, Tugba Basoglu
article en

Abstract

This study is the first to validate the GRIm Score in malignant melanoma, suggesting it is a valuable biomarker for patient selection in immunotherapy trials. The findings highlight its potential in refining treatment decisions, though further validation in larger, multicenter cohorts is required.

Journal of Cancer Research and Clinical OncologyVol. 152(1)
Dr Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi (TR), Sağlık Bilimleri Üniversitesi (TR)
Good health and well-being
Openalex Percentile: Top 94%
Cancer Immunotherapy and Biomarkers
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