Pharmacokinetic properties of insulin <scp>GZR4</scp> after subcutaneous administration in the thigh, abdomen, or upper arm in healthy participants

In healthy Chinese participants, subcutaneous injection of GZR4 in the thigh, abdomen, or upper arm displayed comparable drug exposure, with no clinically meaningful differences observed among the injection regions.

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Publication Details

Journal
Diabetes Obesity and Metabolism
Published
2026-01-08
DOI
https://doi.org/10.1111/dom.70461
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Pharmacokinetic properties of insulin GZR4 after subcutaneous administration in the thigh, abdomen, or upper arm in healthy participants

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Diabetes Obesity and Metabolism
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Pharmacokinetic properties of insulin GZR4 after subcutaneous administration in the thigh, abdomen, or upper arm in healthy participants

Junmin Dong, Chunpu Lei, Yingjuan Zhang, Jing Zhao, Wei Chen, Pu Li, Long Liu, Xiaohua Hao, Fang Cheng, Xiaoqiang Cheng, Yuanxu Tong, Xiaoyun Liu, Wei Zhao
article en

Abstract

In healthy Chinese participants, subcutaneous injection of GZR4 in the thigh, abdomen, or upper arm displayed comparable drug exposure, with no clinically meaningful differences observed among the injection regions.

Diabetes Obesity and MetabolismVol. 28(4)
Luye Pharma (China) (CN), Lee's Pharmaceutical (China) (CN), Beijing Shijitan Hospital (CN)
Openalex Percentile: Top 94%
Diabetes Treatment and Management
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