Seven-Year Surveillance and AI-Based Forecasting of Antimicrobial Resistance in Pediatric Escherichia coli Infections in Northern China (2018–2024)

Pediatric <i>E. coli</i> isolates in our center exhibited high resistance to several common oral agents but encouraging declines in ESBL prevalence and cephalosporin resistance, likely reflecting local antimicrobial stewardship. Exploratory AI-based time-series models may help anticipate resistance trajectories and support pediatric antibiotic policies and stewardship, although forecasts from a short annual series should be interpreted cautiously.