The Impact of Diet, Exercise and Obstructive Sleep Apnea on Atherogenic Erectile Dysfunction: An Expert Review

Erectile dysfunction (ED) is common and becomes more prevalent with age. The most common form of ED, atherogenic, is considered "the canary in the coal mine" for coronary artery disease, as it is a harbinger of angina and myocardial infarction. Given the smaller size of the penile artery relative to the coronary arteries, atherogenic ED often precedes coronary events by 2-5 years. Diet, exercise, and treatment of sleep apnea have the potential to improve and even reverse arteriogenic erectile dysfunction by, in part, decreasing oxidative stress and inflammation, thereby increasing nitric oxide bioavailability and improving vascular function. The potential for lifestyle changes to improve erectile function may prove uniquely motivating for patients to make such changes.

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Publication Details

Journal
American Journal of Lifestyle Medicine
Published
2026-01-08
DOI
https://doi.org/10.1177/15598276251408782
Primary Topic
Sexual function and dysfunction studies
Type
article
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article

The Impact of Diet, Exercise and Obstructive Sleep Apnea on Atherogenic Erectile Dysfunction: An Expert Review

Ashutosh Yaligar, Justin Johannesen, Kathleen Allen, Robert J. Ostfeld et al.
American Journal of Lifestyle Medicine
Sexual function and dysfunction studies
article

The Impact of Diet, Exercise and Obstructive Sleep Apnea on Atherogenic Erectile Dysfunction: An Expert Review

Ashutosh Yaligar, Justin Johannesen, Kathleen Allen, Robert J. Ostfeld, Aaron Spitz, Dean Sherzai, Yoav Jacob, Anika Agarwal, Priyansh Shah, Wai Thein
article en

Abstract

Erectile dysfunction (ED) is common and becomes more prevalent with age. The most common form of ED, atherogenic, is considered "the canary in the coal mine" for coronary artery disease, as it is a harbinger of angina and myocardial infarction. Given the smaller size of the penile artery relative to the coronary arteries, atherogenic ED often precedes coronary events by 2-5 years. Diet, exercise, and treatment of sleep apnea have the potential to improve and even reverse arteriogenic erectile dysfunction by, in part, decreasing oxidative stress and inflammation, thereby increasing nitric oxide bioavailability and improving vascular function. The potential for lifestyle changes to improve erectile function may prove uniquely motivating for patients to make such changes.

American Journal of Lifestyle Medicine
Albert Einstein College of Medicine (US), Jacobi Medical Center (US), University of California System (US), Massachusetts General Hospital (US), Urology Associates (US), Montefiore Health System (US), Charles R. Drew University of Medicine and Science (US)
Openalex Percentile: Top 93%
Sexual function and dysfunction studies
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The Impact of Diet, Exercise and Obstructive Sleep Apnea on Atherogenic Erectile Dysfunction: An Expert Review — Ashutosh Yaligar, Justin Johannesen, et al. · American Journal of Lifestyle Medicine (2026) | TGRS Research Map | TGRS