20 01 Base Architecture Acute Myeloid Leukemia AML

Acute myeloid leukemia (AML) presents a fundamental challenge in oncology: how do malignant cells maintainsurvival and proliferation within the tightly regulated bone marrow microenvironment while evading bothhomeostatic constraints and therapeutic intervention? Traditional approaches focus on genomic aberrationsand isolated cellular pathways, yet AML’s clinical heterogeneity and frequent relapse suggest a more complexsystems-level architecture

Authors

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-01-07
DOI
https://doi.org/10.5281/zenodo.18168091
Primary Topic
Acute Myeloid Leukemia Research
Type
article
Field-Weighted Citation Impact
0.00
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article

20 01 Base Architecture Acute Myeloid Leukemia AML

Ionut Alexandru Stefan
Zenodo (CERN European Organization for Nuclear Research)
Acute Myeloid Leukemia Research
article

20 01 Base Architecture Acute Myeloid Leukemia AML

Ionut Alexandru Stefan
article en

Abstract

Acute myeloid leukemia (AML) presents a fundamental challenge in oncology: how do malignant cells maintainsurvival and proliferation within the tightly regulated bone marrow microenvironment while evading bothhomeostatic constraints and therapeutic intervention? Traditional approaches focus on genomic aberrationsand isolated cellular pathways, yet AML’s clinical heterogeneity and frequent relapse suggest a more complexsystems-level architecture

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Openalex Percentile: Top 94%
Acute Myeloid Leukemia Research
DOIOpen Access PDFOpenAlex
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20 01 Base Architecture Acute Myeloid Leukemia AML — Ionut Alexandru Stefan · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS