Cytomegalovirus colitis in a woman with Sheehan syndrome

This case highlights that CMV colitis can occur in older adults without classical immunosuppressive risk factors and that endocrine disorders such as Sheehan syndrome may contribute to subtle immune impairment. Chronic hypopituitarism combined with long-term glucocorticoid replacement may create a permissive environment for CMV development. Clinicians should consider CMV colitis when evaluating persistent gastrointestinal symptoms in elderly patients with endocrine dysfunction or chronic corticosteroid use.