Multimodal machine learning to predict response to ultrasound-guided botulinum and vibration therapy in muscle spasticity a clinical and imaging correlation study

Ultrasound-guided BTX combined with vibration therapy provides greater improvements in spasticity and functional outcomes compared with BTX alone. Multimodal machine learning models demonstrate potential for predicting individual treatment response, supporting the adjunctive role of ultrasound-derived biomarkers in personalized spasticity management.