Strongyloides stercoralis coinfection impairs immune control of Mycobacterium tuberculosis in TB infected individuals
<i>Ss</i> co-infection impairs host antimycobacterial control by skewing TBI immune responses toward Th2/regulatory pathways at the expense of protective Th1/Th17 mechanisms. Our data demonstrate that the importance of considering <i>Ss</i> co-infection into account when developing TB control and vaccination strategies in endemic areas.
Authors
- Arul Nancy Pandiarajan
- Bindu Dasan
- Saravanan Munisankar
- Sivakumar Shanmugam
- Anuradha Rajamanickam
- Subash Babu
Institutions
- Indian Council of Medical Research (IN)
- International Centers for Excellence in Research (IN)
- National Institute of Allergy and Infectious Diseases (US)
- National Institute of Research in Tuberculosis (IN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-09
- DOI
- https://doi.org/10.3389/fimmu.2025.1735029
- Primary Topic
- Parasites and Host Interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00