The role of 5-methylcytosine regulator-related genes in diagnostic and immune regulatory functions in atherosclerosis

Five potential diagnostic biomarkers for AS-MCL1, F13A1, RGS2, TLR8, and TAGAP-were identified. In addition, the m5C regulator NSUN3 plays a critical role in macrophage function, providing experimental evidence that may support the diagnosis and treatment of AS.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-01-09
DOI
https://doi.org/10.3389/fimmu.2025.1636323
Primary Topic
RNA modifications and cancer
Type
article
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0.00
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article

The role of 5-methylcytosine regulator-related genes in diagnostic and immune regulatory functions in atherosclerosis

Pengfei Ding, Luqun Yang, Ying Kong, Hui Zhao et al.
Frontiers in Immunology
RNA modifications and cancer
article

The role of 5-methylcytosine regulator-related genes in diagnostic and immune regulatory functions in atherosclerosis

Pengfei Ding, Luqun Yang, Ying Kong, Hui Zhao, Ning Li
article en

Abstract

Five potential diagnostic biomarkers for AS-MCL1, F13A1, RGS2, TLR8, and TAGAP-were identified. In addition, the m5C regulator NSUN3 plays a critical role in macrophage function, providing experimental evidence that may support the diagnosis and treatment of AS.

Frontiers in ImmunologyVol. 16
Shanxi Medical University (CN), Shanxi Academy of Medical Sciences (CN)
No poverty
Openalex Percentile: Top 94%
RNA modifications and cancer
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