Comparison of cardiovascular outcomes between once‐weekly semaglutide and dulaglutide in adults with type 2 diabetes and established atherosclerotic cardiovascular disease in the United States

Among United States Medicare Optum CDM enrolees with T2D and ASCVD, semaglutide was associated with reduced risks of CV outcomes compared with dulaglutide. These results help to address an important evidence gap in selecting glucagon-like peptide-1 receptor agonists for this high-risk population.

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Publication Details

Journal
Diabetes Obesity and Metabolism
Published
2026-01-08
DOI
https://doi.org/10.1111/dom.70440
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00

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article

Comparison of cardiovascular outcomes between once‐weekly semaglutide and dulaglutide in adults with type 2 diabetes and established atherosclerotic cardiovascular disease in the United States

CAROLINE SWIFT, Chalak Muhammad, Lin Xie, XI TAN et al.
Diabetes Obesity and Metabolism
Diabetes Treatment and Management
article

Comparison of cardiovascular outcomes between once‐weekly semaglutide and dulaglutide in adults with type 2 diabetes and established atherosclerotic cardiovascular disease in the United States

CAROLINE SWIFT, Chalak Muhammad, Lin Xie, XI TAN, Yuanjie Liang, Adam de Havenon, Cynthia Gutierrez, Joanna Harton
article en

Abstract

Among United States Medicare Optum CDM enrolees with T2D and ASCVD, semaglutide was associated with reduced risks of CV outcomes compared with dulaglutide. These results help to address an important evidence gap in selecting glucagon-like peptide-1 receptor agonists for this high-risk population.

Diabetes Obesity and MetabolismVol. 28(4)
Yale University (US), Novo Nordisk (United States) (US), Yale New Haven Health System (US)
Novo Nordisk
Good health and well-being
Openalex Percentile: Top 94%
Diabetes Treatment and Management
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Comparison of cardiovascular outcomes between once‐weekly semaglutide and dulaglutide in adults with type 2 diabetes and established atherosclerotic cardiovascular disease in the United States — CAROLINE SWIFT, Chalak Muhammad, et al. · Diabetes Obesity and Metabolism (2026) | TGRS Research Map | TGRS