The NGF Nerve Ingrowth Sensitization Cascade

Chronic discogenic low back pain frequently persists independentof structural degeneration severity, suggesting pain mechanisms dissociable fromtissue damage. While nerve growth factor (NGF) and pathological nerve ingrowthare implicated, the system-level organization of this nociceptive pathway remainsunclear.

Authors

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-01-05
DOI
https://doi.org/10.5281/zenodo.18154446
Primary Topic
Pain Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

The NGF Nerve Ingrowth Sensitization Cascade

Ionut Alexandru Stefan
Zenodo (CERN European Organization for Nuclear Research)
Pain Mechanisms and Treatments
article

The NGF Nerve Ingrowth Sensitization Cascade

Ionut Alexandru Stefan
article en

Abstract

Chronic discogenic low back pain frequently persists independentof structural degeneration severity, suggesting pain mechanisms dissociable fromtissue damage. While nerve growth factor (NGF) and pathological nerve ingrowthare implicated, the system-level organization of this nociceptive pathway remainsunclear.

Zenodo (CERN European Organization for Nuclear Research)
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Pain Mechanisms and Treatments
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The NGF Nerve Ingrowth Sensitization Cascade — Ionut Alexandru Stefan · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS