Exploring lung microbiota and clinical application of BALF-mNGS in patients with pulmonary mycobacterial diseases: a multicenter retrospective study
BALF-mNGS not only provides superior pathogen detection in patients with PMDs but also shows that lower MTBC/NTM abundance is associated with better clinical prognosis, including shorter hospital stay and better treatment effectiveness, highlighting its potential role as a prognostic indicator.
Authors
- Jiancheng Zhuge (ORCID: https://orcid.org/0009-0009-2191-5174)
- Wenwei Cai
- Honglong Fang (ORCID: https://orcid.org/0009-0000-9697-5213)
- Xiaojing Zhang (ORCID: https://orcid.org/0000-0002-4964-0960)
- Jin Fu (ORCID: https://orcid.org/0000-0001-7532-784X)
- Lu Sun (ORCID: https://orcid.org/0000-0003-1889-704X)
- Zhidan Hua
- Lu Zhang
- Junjie Zhao
Institutions
- Zhejiang Chinese Medical University (CN)
- Tianjin Economic-Technological Development Area (CN)
- Quzhou City People's Hospital (CN)
- Quzhou University (CN)
- Zhejiang Provincial People's Hospital (CN)
- Hangzhou Medical College (CN)
Publication Details
- Journal
- BMC Microbiology
- Published
- 2026-01-09
- DOI
- https://doi.org/10.1186/s12866-025-04707-9
- Primary Topic
- Mycobacterium research and diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00