Glial fibrillary acidic protein antibody-associated astrocytopathy presents isolated spinal cord enhancement: A case report

This case confirms that GFAP-A can be detected with positive spinal cord MRI findings alone, while negative brain MRI findings. Its key clinical significance lies in emphasizing the diagnostic value of CSF glial fibrillary acidic protein antibody detection for atypical cases, providing a new reference for the imaging spectrum of GFAP-A.

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Publication Details

Journal
Medicine
Published
2026-01-02
DOI
https://doi.org/10.1097/md.0000000000046689
Primary Topic
Autoimmune Neurological Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Glial fibrillary acidic protein antibody-associated astrocytopathy presents isolated spinal cord enhancement: A case report

Ying Guo, Weichao Bao, Yuan Xue, Xiaoyan Du et al.
Medicine
Autoimmune Neurological Disorders and Treatments
article

Glial fibrillary acidic protein antibody-associated astrocytopathy presents isolated spinal cord enhancement: A case report

Ying Guo, Weichao Bao, Yuan Xue, Xiaoyan Du, Xin Zou, Chunxiang Wang
article en

Abstract

This case confirms that GFAP-A can be detected with positive spinal cord MRI findings alone, while negative brain MRI findings. Its key clinical significance lies in emphasizing the diagnostic value of CSF glial fibrillary acidic protein antibody detection for atypical cases, providing a new reference for the imaging spectrum of GFAP-A.

MedicineVol. 105(1)
Weifang Medical University (CN), Second Hospital of Shandong University (CN), Gaozhou People's Hospital (CN), Weifang University (CN)
Good health and well-being
Openalex Percentile: Top 93%
Autoimmune Neurological Disorders and Treatments
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Glial fibrillary acidic protein antibody-associated astrocytopathy presents isolated spinal cord enhancement: A case report — Ying Guo, Weichao Bao, et al. · Medicine (2026) | TGRS Research Map | TGRS