Association of Naples Prognostic Score with Survival in Patients with Inoperable Esophageal Squamous Cell Carcinoma Undergoing Chemoradiotherapy Combined with Immunotherapy

The NPS has been demonstrated to be a reliable prognostic tool in unresectable ESCC. It provides a practical framework for baseline risk stratification at diagnosis to identify high-risk patients who may benefit from intensified nutritional support, closer surveillance, or enrollment in novel immunotherapy trials, thereby guiding personalized treatment and optimizing resource use.