Comparing Vasopressin and Hydrocortisone as Adjunctive Measures in Septic Shock
Administration of hydrocortisone as an adjunct to norepinephrine in septic shock was associated with lower in-hospital mortality compared to vasopressin. The addition of hydrocortisone as the initial adjunct to norepinephrine may improve clinical outcomes in septic shock, and early initiation should be considered in patients with escalating norepinephrine requirements.
Authors
- H C Wang
- Beena Cheriyan
- Sichao Wang (ORCID: https://orcid.org/0000-0003-0931-7883)
- David Sudekum (ORCID: https://orcid.org/0000-0001-5043-7583)
- Marianne Huebner (ORCID: https://orcid.org/0000-0002-9694-9231)
Institutions
- Trinity Health (US)
- Hospital of the University of Pennsylvania (US)
- Michigan State University (US)
Publication Details
- Journal
- Annals of Pharmacotherapy
- Published
- 2026-01-07
- DOI
- https://doi.org/10.1177/10600280251406750
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00