Methionine Restriction Must Be Continuously Maintained to Selectively Inhibit Cancer Cells Co-cultured With Normal Cells

Continuous treatment with rMETase is necessary to maintain inhibition of cancer cells and normal-cell dominance in co-culture with cancer cells. These results have clinical implications indicating that methionine restriction must be continually maintained to inhibit cancer.

Authors

Institutions

Publication Details

Journal
Cancer Diagnosis & Prognosis
Published
2026-01-03
DOI
https://doi.org/10.21873/cdp.10504
Primary Topic
Cancer Research and Treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Methionine Restriction Must Be Continuously Maintained to Selectively Inhibit Cancer Cells Co-cultured With Normal Cells

S LI, Yohei Asano, R. Hoffman, KOHEI MIZUTA et al.
Cancer Diagnosis & Prognosis
Cancer Research and Treatments
article

Methionine Restriction Must Be Continuously Maintained to Selectively Inhibit Cancer Cells Co-cultured With Normal Cells

S LI, Yohei Asano, R. Hoffman, KOHEI MIZUTA, M. Bouvet, Byung Mo Kang, YUTA MIYASHI, JIN SOO KIM, Qinghong Han
article en

Abstract

Continuous treatment with rMETase is necessary to maintain inhibition of cancer cells and normal-cell dominance in co-culture with cancer cells. These results have clinical implications indicating that methionine restriction must be continually maintained to inhibit cancer.

Cancer Diagnosis & PrognosisVol. 6(1)
University of California San Diego (US), AntiCancer (United States) (US)
Good health and well-being
Openalex Percentile: Top 94%
Cancer Research and Treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.