Metabolic consequences of perinatal bisphenol A and 17α-Ethinylestradiol exposure manifest in circadian alterations of energy homeostasis in adult male mice

Maternal exposure to environmentally relevant doses of BPA or EE2 can alter the development and function of metabolic regulatory systems, producing distinct disruptions in circadian energy homeostasis in adult offspring. These differential effects likely reflect the partially overlapping yet distinct organizational and activational pathways through which these endocrine-disrupting chemicals act during the perinatal period.