Right ventricular myocardial performance index as an early marker of cardiac dysfunction in systemic sclerosis

RV MPI was shown to be significantly increased in SSc, even in the absence of overt cardiac symptoms or reduced left ventricular ejection fraction and remained independently associated with SSc. Together with reduced TAPSE and TAPSE/sPAP ratios, these findings indicate impaired RV-pulmonary arterial coupling. RV MPI therefore appears to be a simple and sensitive non-invasive parameter for the identification of cardiac involvement in SSc.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-01-06
DOI
https://doi.org/10.3389/fmed.2025.1722534
Primary Topic
Pulmonary Hypertension Research and Treatments
Type
article
Field-Weighted Citation Impact
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article

Right ventricular myocardial performance index as an early marker of cardiac dysfunction in systemic sclerosis

Veli COBANKARA, Emrah Kaya, Murat Taşçı, Uğur Karasu et al.
Frontiers in Medicine
Pulmonary Hypertension Research and Treatments
article

Right ventricular myocardial performance index as an early marker of cardiac dysfunction in systemic sclerosis

Veli COBANKARA, Emrah Kaya, Murat Taşçı, Uğur Karasu, İlknur Kaya
article en

Abstract

RV MPI was shown to be significantly increased in SSc, even in the absence of overt cardiac symptoms or reduced left ventricular ejection fraction and remained independently associated with SSc. Together with reduced TAPSE and TAPSE/sPAP ratios, these findings indicate impaired RV-pulmonary arterial coupling. RV MPI therefore appears to be a simple and sensitive non-invasive parameter for the identification of cardiac involvement in SSc.

Frontiers in MedicineVol. 12
Chest Diseases Hospital (KW), Sağlık Bilimleri Üniversitesi (TR), Universidad CES (CO), Kutahya Saglik Bilimleri Universitesi, Pamukkale University (TR), Bolu Abant İzzet Baysal University (TR)
Good health and well-being
Openalex Percentile: Top 95%
Pulmonary Hypertension Research and Treatments
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