Spinal astrocytic EAATs mediate endothelin-1-induced breakthrough cancer pain in mice

This optimized ET-1 model provides a robust platform for BTcP research. Spinal EAATs, downregulation and C×43 activation, contribute to BTcP pathogenesis, and both are potential therapeutic targets of BTcP.

Authors

Siqing Jiang (ORCID: https://orcid.org/0000-0002-2328-8372)
Xin Li
Dong Huang
Lihua Huang

Institutions

Central South University (CN)
Third Xiangya Hospital (CN)

Publication Details

Journal: Neurological Research
Published: 2026-01-06
DOI: https://doi.org/10.1080/01616412.2025.2612305
Citations: 1
Primary Topic: Nitric Oxide and Endothelin Effects
Type: article
Field-Weighted Citation Impact: 32.84

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article

Spinal astrocytic EAATs mediate endothelin-1-induced breakthrough cancer pain in mice

Siqing Jiang, Xin Li, Dong Huang, Lihua Huang

Jan 6, 2026

1 citations

Neurological Research

Nitric Oxide and Endothelin Effects

32.84

article

Spinal astrocytic EAATs mediate endothelin-1-induced breakthrough cancer pain in mice

Siqing Jiang, Xin Li, Dong Huang, Lihua Huang

January 6, 2026article en

1 citations

Abstract

Neurological Research

Central South University (CN), Third Xiangya Hospital (CN)

Good health and well-being

Openalex Percentile: Top 2%

Nitric Oxide and Endothelin Effects

32.84

DOI Source OpenAlex

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Spinal astrocytic EAATs mediate endothelin-1-induced breakthrough cancer pain in mice — Siqing Jiang, Xin Li, et al. · Neurological Research (2026) | TGRS Research Map | TGRS