Multisystem challenges in reproductive medicine: A case report of bicornuate uterus, fibroadenoma, and postpartum thyroiditis

This case demonstrates that favorable reproductive outcomes are achievable even in the presence of significant uterine malformation and endocrine comorbidities when care is individualized and multidisciplinary. The temporal relationship between DMPA initiation and postpartum thyroiditis raises a clinically relevant question about progestin-triggered autoimmune thyroid dysfunction, warranting further study. Early imaging and endocrine profiling should be routine in women presenting with recurrent pregnancy loss.

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Publication Details

Journal
Medicine
Published
2026-01-02
DOI
https://doi.org/10.1097/md.0000000000047007
Citations
1
Primary Topic
Gynecological conditions and treatments
Type
article
Field-Weighted Citation Impact
41.10
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article

Multisystem challenges in reproductive medicine: A case report of bicornuate uterus, fibroadenoma, and postpartum thyroiditis

Fatima S. Faisal, H. Siddiqui, N. ANAND, Nana Sardarova et al.
1 citations
Medicine
Gynecological conditions and treatments
41.10
article

Multisystem challenges in reproductive medicine: A case report of bicornuate uterus, fibroadenoma, and postpartum thyroiditis

Fatima S. Faisal, H. Siddiqui, N. ANAND, Nana Sardarova, Fathimathul Henna, Bhumi Daishik Patel, Ahmed Ibrahim, Tirath Patel, Faisal Muzaffar, Aiman Javed
article en
1 citations

Abstract

This case demonstrates that favorable reproductive outcomes are achievable even in the presence of significant uterine malformation and endocrine comorbidities when care is individualized and multidisciplinary. The temporal relationship between DMPA initiation and postpartum thyroiditis raises a clinically relevant question about progestin-triggered autoimmune thyroid dysfunction, warranting further study. Early imaging and endocrine profiling should be routine in women presenting with recurrent pregnancy loss.

MedicineVol. 105(1)
Nishtar Medical College and Hospital (PK), Trinity School of Medicine (VC), Jinnah Sindh Medical University (PK), Windsor University School of Medicine (KN), The University of Texas Rio Grande Valley (US), Dow University of Health Sciences (PK), Michigan Surgical Hospital (US), Dubai Medical College (AE)
Good health and well-being
Openalex Percentile: Top 2%
Gynecological conditions and treatments
41.10
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Multisystem challenges in reproductive medicine: A case report of bicornuate uterus, fibroadenoma, and postpartum thyroiditis — Fatima S. Faisal, H. Siddiqui, et al. · Medicine (2026) | TGRS Research Map | TGRS