Systemic light chain cardiac amyloidosis with atrioventricular block

This case highlights a crucial principle in the management of AL amyloidosis: improvement in hematologic status and cardiac structure/function does not equate to electrophysiologic stability. In high-risk patients, vigilance for occult conduction disease must persist even after clinical recovery. The ICM serves as a pivotal "bridge" tool to detect intermittent, life-threatening bradyarrhythmias and guide timely, precise device-based intervention. These findings underscore the need for individualized, long-term cardiac electrophysiological monitoring strategies in patients with AL-CA.

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Publication Details

Journal
Frontiers in Cardiovascular Medicine
Published
2026-01-08
DOI
https://doi.org/10.3389/fcvm.2025.1573007
Citations
1
Primary Topic
Amyloidosis: Diagnosis, Treatment, Outcomes
Type
article
Field-Weighted Citation Impact
22.24
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article

Systemic light chain cardiac amyloidosis with atrioventricular block

Xiaohong Pan, Jiadan Liao
1 citations
Frontiers in Cardiovascular Medicine
Amyloidosis: Diagnosis, Treatment, Outcomes
22.24
article

Systemic light chain cardiac amyloidosis with atrioventricular block

Xiaohong Pan, Jiadan Liao
article en
1 citations

Abstract

This case highlights a crucial principle in the management of AL amyloidosis: improvement in hematologic status and cardiac structure/function does not equate to electrophysiologic stability. In high-risk patients, vigilance for occult conduction disease must persist even after clinical recovery. The ICM serves as a pivotal "bridge" tool to detect intermittent, life-threatening bradyarrhythmias and guide timely, precise device-based intervention. These findings underscore the need for individualized, long-term cardiac electrophysiological monitoring strategies in patients with AL-CA.

Frontiers in Cardiovascular MedicineVol. 12
The Third Affiliated Hospital of Zhejiang Chinese Medical University (CN), Second Affiliated Hospital of Zhejiang University (CN)
Openalex Percentile: Top 3%
Amyloidosis: Diagnosis, Treatment, Outcomes
22.24
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