The Risk Profile of Face Transplant Versus Other Types of Vascularized Composite Allotransplantation Surgery—A Retrospective Multicenter Analysis
Facial vascularized composite allotransplantation (FVCA) stands out from VCA procedures due to its heightened immunologic complexity and unique clinical challenges, including high antigenicity from the included skin, presensitized patients, and visible grafts. Facial vascularized composite allotransplantation (FVCA) demands stronger immunosuppression and intensive perioperative monitoring to manage complications. Continued efforts to optimize these strategies are crucial to reduce morbidity and improve outcomes, ensuring FVCA's transformative potential is realized safely and effectively.
Authors
- Maxime Jeljeli
- J. H. Dean (ORCID: https://orcid.org/0009-0002-5140-960X)
- Alexandre G. Lellouch (ORCID: https://orcid.org/0000-0001-8191-8662)
- Elena Hofmann (ORCID: https://orcid.org/0000-0003-4458-9278)
- Gabriel Hundeshagen (ORCID: https://orcid.org/0000-0002-6173-8602)
- Curtis L. Cetrulo (ORCID: https://orcid.org/0000-0001-7080-3894)
- Steffen Koerdt (ORCID: https://orcid.org/0000-0002-8679-8775)
- Benedikt Geldner (ORCID: https://orcid.org/0009-0008-5461-6835)
- Tobias Niederegger (ORCID: https://orcid.org/0009-0004-3065-4352)
- Thomas Schaschinger (ORCID: https://orcid.org/0009-0000-6523-1641)
- Max Heiland
- Leonard Knoedler
Institutions
- Cedars-Sinai Medical Center (US)
- Harvard University (US)
- University of Pittsburgh (US)
- Heidelberg University (DE)
- Ludwigshafen University of Business and Society (DE)
- Humboldt-Universität zu Berlin (DE)
- Massachusetts General Hospital (US)
- Klinikum Ludwigshafen (DE)
Publication Details
- Journal
- Journal of Craniofacial Surgery
- Published
- 2026-01-06
- DOI
- https://doi.org/10.1097/scs.0000000000012358
- Primary Topic
- Organ and Tissue Transplantation Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00