Cardamonin induces apoptosis of colorectal cancer cells via targeted inhibition of the JAK/STAT3/epithelial-mesenchymal transition (EMT) signaling axis

CDN inhibits CRC progression and induces apoptosis by targeting the JAK/STAT3/EMT signaling axis, suggesting that CDN is a promising therapeutic agent for CRC.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2026-01-08
DOI
https://doi.org/10.3389/fphar.2025.1739201
Primary Topic
Ginger and Zingiberaceae research
Type
article
Field-Weighted Citation Impact
0.00

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article

Cardamonin induces apoptosis of colorectal cancer cells via targeted inhibition of the JAK/STAT3/epithelial-mesenchymal transition (EMT) signaling axis

Mengqi Wu, Wenhu Liu, Chuan Chen, Zhenzhong Liu et al.
Frontiers in Pharmacology
Ginger and Zingiberaceae research
article

Cardamonin induces apoptosis of colorectal cancer cells via targeted inhibition of the JAK/STAT3/epithelial-mesenchymal transition (EMT) signaling axis

Mengqi Wu, Wenhu Liu, Chuan Chen, Zhenzhong Liu, Dan Ren, Zuo Du
article en

Abstract

CDN inhibits CRC progression and induces apoptosis by targeting the JAK/STAT3/EMT signaling axis, suggesting that CDN is a promising therapeutic agent for CRC.

Frontiers in PharmacologyVol. 16
North Sichuan Medical University (CN)
Strong
Good health and well-being
Openalex Percentile: Top 94%
Ginger and Zingiberaceae research
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