Asymmetric synthesis of 4,5-dihydropyrrole derivatives <i>via</i> DKR: DROC of activated aziridines with enaminones
An efficient and highly enantioselective route to 4,5-dihydropyrrole derivatives via DKR assisted domino ring opening cyclization DROC of racemic aziridines with N , N -dimethyl enaminones employing Cu( i )-( S )-XylBINAP as the catalyst system is reported.
Authors
- Poulami Mandal (ORCID: https://orcid.org/0000-0001-8903-7907)
- Nilay Kumar Pal (ORCID: https://orcid.org/0000-0003-4824-463X)
- Ranjan Mali
- Noimur Rahman
- Manas K. Ghorai
- Amit Kumar Sharma
Institutions
- Indian Institute of Technology Kanpur (IN)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1039/d5qo01590a
- Primary Topic
- Synthesis and Characterization of Pyrroles
- Type
- article
- Field-Weighted Citation Impact
- 0.00