The critical relationship between tacrolimus levels, acute kidney injury, and early chronic lung allograft dysfunction
Our data suggest that a transient decline in TAC serum concentrations, often caused by a TAC-induced AKI, may trigger the onset of CLAD10 and subsequently elevate the risk of premature death.
Authors
- Luca Kohlhepp
- Ignaz Briegel (ORCID: https://orcid.org/0000-0002-8733-5385)
- Dominik J. Hoechter (ORCID: https://orcid.org/0000-0003-4026-5137)
- Tobias Veit (ORCID: https://orcid.org/0000-0002-4117-0175)
- Jürgen Barton
- B. M. Meiser
- Roman Hauber (ORCID: https://orcid.org/0000-0002-1655-2307)
- Teresa Kauke (ORCID: https://orcid.org/0000-0001-6569-9703)
- Christian Schneider (ORCID: https://orcid.org/0000-0003-4501-3094)
- Jürgen Behr (ORCID: https://orcid.org/0000-0002-9151-4829)
- Nikolaus Kneidinger
- Rudolf Hatz
Institutions
- Medical University of Graz (AT)
- University of Würzburg (DE)
- LMU Klinikum (DE)
- German Center for Lung Research (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Frontiers in Transplantation
- Published
- 2026-01-07
- DOI
- https://doi.org/10.3389/frtra.2025.1704682
- Primary Topic
- Transplantation: Methods and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsches Zentrum für Lungenforschung