Interpreting Neonatal <scp>hyperCKemia</scp> Identified Through Duchenne Muscular Dystrophy Newborn Screening: A Predictive Model Based on Maternal, Labor, Delivery and Newborn Factors
Elevated CK levels may be used for DMD-NBS. Multiple perinatal factors are associated with transient non-DMD hyperCKemia. Our model considers the potential combined impact of such factors and generates a non-disease likelihood for preliminary hyperCKemia interpretation.
Authors
- Sara Cherkerzian
- Yvonne Sheldon
- Stephen M. Chrzanowski (ORCID: https://orcid.org/0000-0003-4321-5661)
- Richard B. Parad (ORCID: https://orcid.org/0000-0002-4326-0609)
- Francis Coyne
- Elisa N. Falk
Institutions
- Brigham and Women's Hospital (US)
- Boston Children's Hospital (US)
- University of Massachusetts Chan Medical School (US)
Publication Details
- Journal
- Muscle & Nerve
- Published
- 2026-01-07
- DOI
- https://doi.org/10.1002/mus.70089
- Primary Topic
- Muscle Physiology and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00