Fungal-specific IgG responses in allergic conjunctivitis: comparison with IgE and immunological implications

Serum fungus-specific IgG antibodies may serve as useful biomarkers reflecting the severity of allergic conjunctivitis. Given that mucosal barrier dysfunction has been implicated in allergic inflammation, the findings suggest that hypersensitivity reactions to fungal elements due to impaired barrier function may contribute to disease pathogenesis.