Temporal dynamics of IgM and IgG after COVID-19 vaccination: a pilot cohort study on breakthrough infections
These findings suggest that, in the early stages following vaccination, the immune system may experience a temporary "immune trough," potentially even below pre-vaccination levels. As a result, individuals should exercise additional caution during this period to mitigate infection risk.
Authors
- X. Chen
- Berthold HOCHER
- Xitong Li (ORCID: https://orcid.org/0009-0003-3060-282X)
- Jingyun Wang (ORCID: https://orcid.org/0000-0002-9073-2349)
- Yaochen Cao
Institutions
- Central South University (CN)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- Reproductive & Genetic Hospital CITIC-Xiangya (CN)
- CS Diagnostics (DE)
- University Medical Centre Mannheim (DE)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Clinical and Experimental Vaccine Research
- Published
- 2026-01-01
- DOI
- https://doi.org/10.7774/cevr.2026.15.e7
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00