HLA and T-Cell Receptor Investigations in Idiopathic and Paraneoplastic Opsoclonus-Myoclonus in Children
Despite similar clinical presentations, idiopathic and paraneoplastic OMASs appear to have distinct immunopathogenic mechanisms. In paraneoplastic OMAS, enrichment of specific HLA antigens and convergent TCR profiles supports antigen-driven T cell-mediated autoimmunity.
Authors
- Elianet Fonseca (ORCID: https://orcid.org/0000-0002-3613-3185)
- Eva Palou
- Lídia Sabater (ORCID: https://orcid.org/0000-0001-8556-6166)
- Gemma Olivé-Cirera (ORCID: https://orcid.org/0000-0002-0880-4260)
- Estibaliz Maudes (ORCID: https://orcid.org/0000-0003-1723-042X)
- Raquel Ruiz García
- JOSEP DALMAU
- Thaís Armangué (ORCID: https://orcid.org/0000-0001-6192-6171)
- Azucena González
- Juan Francisco Luchoro
- Eugenia Martínez-Hernández
- Sergio Aguilera-Albesa
- Guillermo Muñoz-Sánchez
Institutions
- Hospital Sant Joan de Déu Barcelona (ES)
- Hospital de Sant Pau (ES)
- Hospital Clínic de Barcelona (ES)
- Navarrabiomed (ES)
- ERN GUARD-Heart (NL)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- Universitat de Barcelona (ES)
- University of Pennsylvania (US)
Publication Details
- Journal
- Neurology Neuroimmunology & Neuroinflammation
- Published
- 2026-01-07
- DOI
- https://doi.org/10.1212/nxi.0000000000200541
- Primary Topic
- Autoimmune Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00