Binding of IgA1 and surface-expressed collagen-binding protein of Streptococcus mutans contributes to IgA nephropathy pathogenesis

Taken together, it is considered that following invasion into the bloodstream, Cnm binds to and forms a complex with IgA1, leading to deposition of IgA1 in renal glomeruli.

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Publication Details

Journal
Frontiers in Cellular and Infection Microbiology
Published
2026-01-07
DOI
https://doi.org/10.3389/fcimb.2025.1673581
Primary Topic
Renal Diseases and Glomerulopathies
Type
article
Field-Weighted Citation Impact
0.00
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article

Binding of IgA1 and surface-expressed collagen-binding protein of Streptococcus mutans contributes to IgA nephropathy pathogenesis

K. Nakano, M. Matsumoto-Nakano, Yasuyuki Nagasawa, Seigo Ito et al.
Frontiers in Cellular and Infection Microbiology
Renal Diseases and Glomerulopathies
article

Binding of IgA1 and surface-expressed collagen-binding protein of Streptococcus mutans contributes to IgA nephropathy pathogenesis

K. Nakano, M. Matsumoto-Nakano, Yasuyuki Nagasawa, Seigo Ito, Taro Misaki, Yuto Suehiro, Daiki Matsuoka, Ryota Nomura, S Naka, Kana Suehara
article en

Abstract

Taken together, it is considered that following invasion into the bloodstream, Cnm binds to and forms a complex with IgA1, leading to deposition of IgA1 in renal glomeruli.

Frontiers in Cellular and Infection MicrobiologyVol. 15
Hiroshima University (JP), Osaka Gakuin University (JP), Hyogo Medical University (JP), Seirei Christopher University (JP), Okayama University (JP), Seirei Hamamatsu General Hospital (JP), Self-Defense Forces Central Hospital (JP), Hyogo University (JP), The University of Osaka (JP)
Openalex Percentile: Top 95%
Renal Diseases and Glomerulopathies
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Binding of IgA1 and surface-expressed collagen-binding protein of Streptococcus mutans contributes to IgA nephropathy pathogenesis — K. Nakano, M. Matsumoto-Nakano, et al. · Frontiers in Cellular and Infection Microbiology (2026) | TGRS Research Map | TGRS