Recurrent Diffuse Chorioamniotic Hemosiderosis of the Placenta in a Mother With Congenital Heart Disease
A woman in her mid-20s with repaired congenital heart disease (CHD) delivered a 33-week neonate in 2024 following preterm labor and a 24-week neonate in 2025 for non-reassuring fetal heart tones. Placental examination in both cases revealed grossly abnormal, red-brown discolored membranes with a circumvallate insertion. Histologic evaluation demonstrated diffuse chorioamniotic hemosiderosis (DCH) in both cases. This report describes a novel case of recurrent DCH in a mother with CHD and proposes that Fontan physiology may contribute to impaired uteroplacental perfusion, increasing the risk for marginal hemorrhage.
Authors
- H.M. Keir (ORCID: https://orcid.org/0009-0002-4512-1984)
- Charlotte F. Kim
Institutions
- Texas Children's Hospital (US)
Publication Details
- Journal
- Pediatric and Developmental Pathology
- Published
- 2026-01-05
- DOI
- https://doi.org/10.1177/10935266251404118
- Primary Topic
- Maternal and fetal healthcare
- Type
- article
- Field-Weighted Citation Impact
- 0.00