Emulating a Randomized Controlled Trial of Long‐Acting Insulins and Cardiovascular Events Using Real‐World Data for Patients With Type 2 Diabetes

The risk of MACE among patients with T2DM newly prescribed insulin degludec compared to insulin glargine was consistent between the overall population and the DEVOTE eligible subpopulation, while the DEVOTE ineligible population had discrepant point estimates.

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Publication Details

Journal
Pharmacoepidemiology and Drug Safety
Published
2026-01-01
DOI
https://doi.org/10.1002/pds.70313
Primary Topic
Diabetes Management and Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Emulating a Randomized Controlled Trial of Long‐Acting Insulins and Cardiovascular Events Using Real‐World Data for Patients With Type 2 Diabetes

W Wang, Vanessa C. Brunetti, Kristian B. Filion, Oriana H. Y. Yu et al.
Pharmacoepidemiology and Drug Safety
Diabetes Management and Research
article

Emulating a Randomized Controlled Trial of Long‐Acting Insulins and Cardiovascular Events Using Real‐World Data for Patients With Type 2 Diabetes

W Wang, Vanessa C. Brunetti, Kristian B. Filion, Oriana H. Y. Yu, Pauline Reynier, Michael Webster‐Clark
article en

Abstract

The risk of MACE among patients with T2DM newly prescribed insulin degludec compared to insulin glargine was consistent between the overall population and the DEVOTE eligible subpopulation, while the DEVOTE ineligible population had discrepant point estimates.

Pharmacoepidemiology and Drug SafetyVol. 35(1)
Jewish General Hospital (CA), Amgen (United Kingdom) (GB), McGill University (CA)
McGill University, Canadian Institutes of Health Research
Good health and well-being
Openalex Percentile: Top 94%
Diabetes Management and Research
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