Hospital production of a 1% propofol–cyclodextrin formulation to address drug shortages: a proof of concept
This study demonstrates the feasibility of a hospital-based preparation of a sterile injectable propofol solution using cyclodextrins. These results support the role of hospital pharmacies in addressing drug shortages by enabling locally controlled and resilient production capacity.
Authors
- Marine Roche
- Laura Négrier (ORCID: https://orcid.org/0000-0001-9879-5347)
- Gilles Lebuffe
- Pascal Odou (ORCID: https://orcid.org/0000-0003-1555-6530)
- Myriam Bouchfaa
- Damien Rousseleau (ORCID: https://orcid.org/0000-0002-9118-8840)
- Nathalie Azaroual
- Cécile Danel
Institutions
- Université de Lille (FR)
- Centre Hospitalier Universitaire de Lille (FR)
- Lille’s Cardiology Hospital (FR)
- Groupe Hospitalier de l'Institut Catholique de Lille (FR)
Publication Details
- Journal
- European Journal of Hospital Pharmacy
- Published
- 2026-01-06
- DOI
- https://doi.org/10.1136/ejhpharm-2025-004779
- Primary Topic
- Pharmaceutical Economics and Policy
- Type
- article
- Field-Weighted Citation Impact
- 0.00