E-liquid flavor alters nicotine exposure, puff topography, and subjective effects under ad libitum use conditions
Tobacco flavor ENDS were rated lower on liking, and associated with less nicotine exposure and fewer puffs taken, but comparably attenuated withdrawal symptoms to other flavor ENDS, while the non-nicotine fruit flavor did not affect withdrawal symptoms.
Authors
- Megan J. Schroeder
- Conor A. Ruzycki (ORCID: https://orcid.org/0000-0002-5055-551X)
- Carolina Ramôa
- Arit M. Harvanko (ORCID: https://orcid.org/0000-0002-1514-4862)
- Jacob D. McDonald
- Eric D. Claus (ORCID: https://orcid.org/0000-0002-1800-0813)
Institutions
- Lovelace Respiratory Research Institute (US)
- Pennsylvania State University (US)
- United States Food and Drug Administration (US)
- Center for Drug Evaluation and Research (US)
Publication Details
- Journal
- Addictive Behaviors Reports
- Published
- 2026-01-06
- DOI
- https://doi.org/10.1016/j.abrep.2026.100665
- Primary Topic
- Sensory Analysis and Statistical Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00