Nuclear cell-free DNA on the loose: an early warning signal of ischemia–reperfusion injury in kidney transplantation
Immediate nuclear cellfree DNA release upon reperfusion reflects intragraft injury linked to downstream thromboinflammatory activation, underscoring the impact of early ischemia-reperfusion injury.
Authors
- Anders Christensson (ORCID: https://orcid.org/0000-0002-7328-8418)
- Mårten Segelmark (ORCID: https://orcid.org/0000-0002-1221-0772)
- Rebecca Trattner
- Myriam Martin (ORCID: https://orcid.org/0000-0003-1526-8678)
- Sharmila Alam
- Oleg Slivca
- Carl M. Öberg (ORCID: https://orcid.org/0000-0002-2471-6914)
- Anna Marie Blom (ORCID: https://orcid.org/0000-0002-1348-1734)
- Ali-Reza Biglarnia
- Bo Nilsson
- Carl J. Raihle
- Clara Paul
- Gabriel Strandberg
Institutions
- Uppsala University (SE)
- University of Calgary (CA)
- Malmö University (SE)
- Lund University (SE)
- Science for Life Laboratory (SE)
- University Hospital of Umeå (SE)
- Malmö Municipality (SE)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-07
- DOI
- https://doi.org/10.3389/fimmu.2025.1704152
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00