Neurobiological Correlates of Behavioral Resilience to Chronic Alcohol and Acute Stress in Male and Female Rats
Our conditioned inhibition task for fear and reward uncovered nuanced patterns of behavioral regulation in response to fear, reward, and inhibitory cues, particularly when these cues were presented concurrently. These patterns enabled the classification of resilient versus non-resilient phenotypes, which were linked to distinct shifts in correlation profiles among interneuron subtypes.
Authors
- Susan Sangha (ORCID: https://orcid.org/0000-0002-6461-4146)
- David P. Lyvers
- Ayelet Kleinerman
- Izabela Caliman
- Jennifer S Mangrum
Institutions
- University School (US)
- Indiana University School of Medicine
- Indiana University (US)
Publication Details
- Journal
- bioRxiv (Cold Spring Harbor Laboratory)
- Published
- 2026-01-07
- DOI
- https://doi.org/10.64898/2026.01.06.697997
- Primary Topic
- Neurotransmitter Receptor Influence on Behavior
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute of Mental Health