Neurobiological Correlates of Behavioral Resilience to Chronic Alcohol and Acute Stress in Male and Female Rats

Our conditioned inhibition task for fear and reward uncovered nuanced patterns of behavioral regulation in response to fear, reward, and inhibitory cues, particularly when these cues were presented concurrently. These patterns enabled the classification of resilient versus non-resilient phenotypes, which were linked to distinct shifts in correlation profiles among interneuron subtypes.

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Publication Details

Journal
bioRxiv (Cold Spring Harbor Laboratory)
Published
2026-01-07
DOI
https://doi.org/10.64898/2026.01.06.697997
Primary Topic
Neurotransmitter Receptor Influence on Behavior
Type
article
Field-Weighted Citation Impact
0.00

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article

Neurobiological Correlates of Behavioral Resilience to Chronic Alcohol and Acute Stress in Male and Female Rats

Susan Sangha, David P. Lyvers, Ayelet Kleinerman, Izabela Caliman et al.
bioRxiv (Cold Spring Harbor Laboratory)
Neurotransmitter Receptor Influence on Behavior
article

Neurobiological Correlates of Behavioral Resilience to Chronic Alcohol and Acute Stress in Male and Female Rats

Susan Sangha, David P. Lyvers, Ayelet Kleinerman, Izabela Caliman, Jennifer S Mangrum
article en

Abstract

Our conditioned inhibition task for fear and reward uncovered nuanced patterns of behavioral regulation in response to fear, reward, and inhibitory cues, particularly when these cues were presented concurrently. These patterns enabled the classification of resilient versus non-resilient phenotypes, which were linked to distinct shifts in correlation profiles among interneuron subtypes.

bioRxiv (Cold Spring Harbor Laboratory)
University School (US), Indiana University School of Medicine, Indiana University (US)
National Institute of Mental Health
Gender equality
Openalex Percentile: Top 94%
Neurotransmitter Receptor Influence on Behavior
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