Ferulic acid in combination with ginsenoside Rb1 alleviates myocardial no-reflow by inhibiting platelet HMGB1 release and NET formation
The combination of FA and Rb1 not only inhibits platelet HMGB1 release but also reduces NETs, thereby enhancing anti-NR efficacy. These findings propose a novel therapeutic approach involving FA-Rb1 combination therapy for alleviating myocardial NR.
Authors
- Shunli Xiao
- Yun You (ORCID: https://orcid.org/0000-0002-7766-1988)
- Yue You
- Jing Xu
- Fulong Liao
- Yilin Wang
- Huamin Zhang
- Xiaojie Yin
- Jialu Zou
- Jia Li
Institutions
- Hunan University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2026-01-08
- DOI
- https://doi.org/10.1186/s13020-025-01303-x
- Primary Topic
- Advanced Glycation End Products research
- Type
- article
- Field-Weighted Citation Impact
- 0.00