Evaluation of Melanin Changes in Acute Vogt–Koyanagi–Harada Disease Using Polarization-Sensitive Optical Coherence Tomography

PS-OCT revealed that choroidal melanin density decreased during the acute phase of VKH disease and significantly increased after treatment. PS-OCT provides a noninvasive method for observing melanin dynamics in VKH disease and aids in differentiating it from posterior scleritis. PS-OCT could offer valuable insights into the pathology of VKH disease and its potential implications for management.

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Publication Details

Journal
Investigative Ophthalmology & Visual Science
Published
2026-01-06
DOI
https://doi.org/10.1167/iovs.67.1.7
Primary Topic
Ocular Diseases and Behçet’s Syndrome
Type
article
Field-Weighted Citation Impact
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OCT
article

Evaluation of Melanin Changes in Acute Vogt–Koyanagi–Harada Disease Using Polarization-Sensitive Optical Coherence Tomography

Kota Totani, Masahiro Yamanari, Naoya Imanaga, Satoshi Sugiyama et al.
Investigative Ophthalmology & Visual Science
Ocular Diseases and Behçet’s Syndrome
article

Evaluation of Melanin Changes in Acute Vogt–Koyanagi–Harada Disease Using Polarization-Sensitive Optical Coherence Tomography

Kota Totani, Masahiro Yamanari, Naoya Imanaga, Satoshi Sugiyama, Nobuhiro Terao, Ayano Oshiro, Hideki Koizumi
article en

Abstract

PS-OCT revealed that choroidal melanin density decreased during the acute phase of VKH disease and significantly increased after treatment. PS-OCT provides a noninvasive method for observing melanin dynamics in VKH disease and aids in differentiating it from posterior scleritis. PS-OCT could offer valuable insights into the pathology of VKH disease and its potential implications for management.

Investigative Ophthalmology & Visual ScienceVol. 67(1)
University of the Ryukyus (JP), Tomey (Japan) (JP)
Good health and well-being
Openalex Percentile: Top 94%
Ocular Diseases and Behçet’s Syndrome
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