Evaluation of Melanin Changes in Acute Vogt–Koyanagi–Harada Disease Using Polarization-Sensitive Optical Coherence Tomography
PS-OCT revealed that choroidal melanin density decreased during the acute phase of VKH disease and significantly increased after treatment. PS-OCT provides a noninvasive method for observing melanin dynamics in VKH disease and aids in differentiating it from posterior scleritis. PS-OCT could offer valuable insights into the pathology of VKH disease and its potential implications for management.
Authors
- Kota Totani
- Masahiro Yamanari (ORCID: https://orcid.org/0000-0001-9873-2151)
- Naoya Imanaga
- Satoshi Sugiyama (ORCID: https://orcid.org/0000-0001-6248-6411)
- Nobuhiro Terao
- Ayano Oshiro (ORCID: https://orcid.org/0000-0001-9220-063X)
- Hideki Koizumi
Institutions
- University of the Ryukyus (JP)
- Tomey (Japan) (JP)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2026-01-06
- DOI
- https://doi.org/10.1167/iovs.67.1.7
- Primary Topic
- Ocular Diseases and Behçet’s Syndrome
- Type
- article
- Field-Weighted Citation Impact
- 0.00