Electroacupuncture Alleviates Oxidative Stress and Cuproptosis in Metabolic Dysfunction-Associated Steatotic Liver Disease Mice Through Activation of the NRF2/ARE Pathway

EA ameliorates MASLD through multiple mechanisms, including regulating lipid metabolism, attenuating inflammation and oxidative stress, activating NRF2, suppressing cuproptosis, and altering the gut-liver axis, collectively contributing to hepatic improvement.

Authors

Xi Tang
Hejing Liu
S H Zhang
Yan Yang (ORCID: https://orcid.org/0000-0001-8146-8040)
Chenglin Tang (ORCID: https://orcid.org/0000-0002-9628-9616)
Mei Liao (ORCID: https://orcid.org/0000-0002-3292-0931)
Cai Liao
Xiao Guo
Junyuan Deng
Kehan Xing
Yunhao Yang

Institutions

Chongqing University (CN)
Chongqing Medical University (CN)

Publication Details

Journal: Diabetes Metabolic Syndrome and Obesity
Published: 2026-01-01
DOI: https://doi.org/10.2147/dmso.s568066
Primary Topic: Liver Disease Diagnosis and Treatment
Type: article
Field-Weighted Citation Impact: 0.00

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article

Electroacupuncture Alleviates Oxidative Stress and Cuproptosis in Metabolic Dysfunction-Associated Steatotic Liver Disease Mice Through Activation of the NRF2/ARE Pathway

Xi Tang, Hejing Liu, S H Zhang, Yan Yang et al.

Jan 1, 2026

Diabetes Metabolic Syndrome and Obesity

Liver Disease Diagnosis and Treatment

article

Electroacupuncture Alleviates Oxidative Stress and Cuproptosis in Metabolic Dysfunction-Associated Steatotic Liver Disease Mice Through Activation of the NRF2/ARE Pathway

Xi Tang, Hejing Liu, S H Zhang, Yan Yang, Chenglin Tang, Mei Liao, Cai Liao, Xiao Guo, Junyuan Deng, Kehan Xing, Yunhao Yang

January 1, 2026article en

Abstract

EA ameliorates MASLD through multiple mechanisms, including regulating lipid metabolism, attenuating inflammation and oxidative stress, activating NRF2, suppressing cuproptosis, and altering the gut-liver axis, collectively contributing to hepatic improvement.

Diabetes Metabolic Syndrome and ObesityVol. Volume 19

Chongqing University (CN), Chongqing Medical University (CN)

Good health and well-being

Openalex Percentile: Top 95%

Liver Disease Diagnosis and Treatment

DOI Open Access PDF OpenAlex

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Electroacupuncture Alleviates Oxidative Stress and Cuproptosis in Metabolic Dysfunction-Associated Steatotic Liver Disease Mice Through Activation of the NRF2/ARE Pathway — Xi Tang, Hejing Liu, et al. · Diabetes Metabolic Syndrome and Obesity (2026) | TGRS Research Map | TGRS