Tacrolimus Assay Comparison: Analytical and Operational Considerations for Immunoassay vs Mass Spectrometry Testing in a High Volume Clinical Laboratory
We observed excellent correlation between the Roche Elecsys tacrolimus assay on an e801 analyzer vs our in-house LC-MS/MS assay, with good precision and linearity across reportable ranges. Changing from mass spectrometry to tacrolimus immunoassay substantially improved our TAT and workflow.
Authors
- Melissa M. Budelier (ORCID: https://orcid.org/0000-0002-1779-5757)
- Florencia A. Monge
- Rebekah Goldblatt
- Cory Hansen
Institutions
- University of New Mexico (US)
- Sandia National Laboratories (US)
Publication Details
- Journal
- The Journal of Applied Laboratory Medicine
- Published
- 2025-12-09
- DOI
- https://doi.org/10.1093/jalm/jfaf199
- Primary Topic
- Renal Transplantation Outcomes and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00