Association of monocyte-lymphocyte ratio with peripheral arterial disease in US participants: a retrospective cross-sectional study

This nationally representative analysis identifies a threshold-based association between MLR and PAD. Despite substantial confounding by age, elevated MLR-particularly in the highest tertile-remains an independent indicator of increased PAD risk, supporting its potential utility in clinical risk assessment.

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Publication Details

Journal
Frontiers in Cardiovascular Medicine
Published
2026-01-08
DOI
https://doi.org/10.3389/fcvm.2025.1613138
Primary Topic
Inflammatory Biomarkers in Disease Prognosis
Type
article
Field-Weighted Citation Impact
0.00

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article

Association of monocyte-lymphocyte ratio with peripheral arterial disease in US participants: a retrospective cross-sectional study

Qiang Liu, Xing Wu, Jianjun Shi
Frontiers in Cardiovascular Medicine
Inflammatory Biomarkers in Disease Prognosis
article

Association of monocyte-lymphocyte ratio with peripheral arterial disease in US participants: a retrospective cross-sectional study

Qiang Liu, Xing Wu, Jianjun Shi
article en

Abstract

This nationally representative analysis identifies a threshold-based association between MLR and PAD. Despite substantial confounding by age, elevated MLR-particularly in the highest tertile-remains an independent indicator of increased PAD risk, supporting its potential utility in clinical risk assessment.

Frontiers in Cardiovascular MedicineVol. 12
Shanxi Medical University (CN), Taiyuan Central Hospital (CN)
General Hospital of People’s Liberation Army
Openalex Percentile: Top 95%
Inflammatory Biomarkers in Disease Prognosis
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