Evaluation of the causal effects of PFOS on atherosclerosis and its potential toxicological mechanisms: Integrated Mendelian randomization and network toxicology analysis
Combining MR with network toxicology analysis, this study investigates the causal relationship between PFOS and AS as well as the underlying toxicological mechanisms, thereby providing scientific evidence and theoretical support for assessing PFOS-induced cardiovascular toxicity and preventing and treating related diseases.
Authors
- Y T Gong
- Cong Yan
- Ning Fang
Institutions
- Harbin Medical University (CN)
- First Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- Ecotoxicology and Environmental Safety
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1016/j.ecoenv.2025.119618
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00