Case Report: NGS-guided rapid diagnosis of tuberculous otitis media—a rare case of dual-site Mycobacterium tuberculosis infection
This case highlights that unexplained hearing loss may serve as an early indicator of disseminated tuberculosis. High-throughput sequencing of aural discharge enables rapid diagnosis of TOM, facilitates resistance-guided treatment, and helps trace the pathways of pathogen transmission.
Authors
- Chi Zhu
- Xin Wen Dong (ORCID: https://orcid.org/0000-0003-3709-0655)
- Yi Cheng
- Xinlei Wang
- Shengxin Ye
- Yang Gao
Institutions
- Changshu No.1 People's Hospital (CN)
- Heze Municipal Hospital (CN)
- Hangzhou Medical College (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-01-08
- DOI
- https://doi.org/10.3389/fmed.2025.1734666
- Primary Topic
- Infectious Diseases and Tuberculosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00