FLASH-therapy suitable single-pulse proton generation using TiH2 under nanosecond laser irradiation

We investigated proton emission from titanium hydride (TiH2) targets irradiated in vacuum by a 6-ns, 1064-nm Nd:YAG laser. Time-of-flight measurements with a Faraday cup and an electrostatic ion analyzer resolved distinct proton peaks at high pulse energies, with yields on the order of 109 protons per shot. Systematic scans over pulse energy and up to 1000 repeated shots showed that, while the peak amplitude gradually decreased, the integrated proton number remained nearly constant. This behavior is consistent with surface-induced broadening of the plasma expansion while bulk hydrogen is replenished by diffusion and repeated ablation of fresh TiH2 layers. Using the measured proton numbers and pulse widths, a simple direct-plasma-injection-style scaling indicates peak currents of ∼100 mA and sub-microsecond pulse durations. The pulse structure and yield satisfy key ultra-high-dose-rate criteria and, together with sustained output over 1000 shots, support TiH2-based laser ion sources as practical candidates for FLASH-therapy (ultra-high-dose-rate)-oriented studies and injector development using direct plasma injection.

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Publication Details

Journal
Review of Scientific Instruments
Published
2026-01-01
DOI
https://doi.org/10.1063/5.0303349
Primary Topic
Laser-Plasma Interactions and Diagnostics
Type
article
Field-Weighted Citation Impact
0.00

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article

FLASH-therapy suitable single-pulse proton generation using TiH2 under nanosecond laser irradiation

Toshiro Sakabe, M. Okamura, T. Kanesue, Shunsuke Ikeda et al.
Review of Scientific Instruments
Laser-Plasma Interactions and Diagnostics
article

FLASH-therapy suitable single-pulse proton generation using TiH2 under nanosecond laser irradiation

Toshiro Sakabe, M. Okamura, T. Kanesue, Shunsuke Ikeda, Shotaro Matsui
article en

Abstract

We investigated proton emission from titanium hydride (TiH2) targets irradiated in vacuum by a 6-ns, 1064-nm Nd:YAG laser. Time-of-flight measurements with a Faraday cup and an electrostatic ion analyzer resolved distinct proton peaks at high pulse energies, with yields on the order of 109 protons per shot. Systematic scans over pulse energy and up to 1000 repeated shots showed that, while the peak amplitude gradually decreased, the integrated proton number remained nearly constant. This behavior is consistent with surface-induced broadening of the plasma expansion while bulk hydrogen is replenished by diffusion and repeated ablation of fresh TiH2 layers. Using the measured proton numbers and pulse widths, a simple direct-plasma-injection-style scaling indicates peak currents of ∼100 mA and sub-microsecond pulse durations. The pulse structure and yield satisfy key ultra-high-dose-rate criteria and, together with sustained output over 1000 shots, support TiH2-based laser ion sources as practical candidates for FLASH-therapy (ultra-high-dose-rate)-oriented studies and injector development using direct plasma injection.

Review of Scientific InstrumentsVol. 97(1)
Brookhaven National Laboratory (US), The University of Osaka (JP)
U.S. Department of Energy, Office of Science, High Energy Physics
Affordable and clean energy
Openalex Percentile: Top 91%
Laser-Plasma Interactions and Diagnostics
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