Novel <i>myo</i> -inositol to butyrate fermentation pathway in the prevalent human gut species <i>Dysosmobacter welbionis,</i> a bacterium associated with improved metabolic and liver health
<i>D. welbionis</i> possesses a unique, conserved route to convert dietary <i>myo</i>-inositol into butyrate, distinguishing it from other commensals and supporting its potential as a next-generation probiotic for metabolic and liver health.
Authors
- Antonio Dario Troise (ORCID: https://orcid.org/0000-0001-7635-5244)
- Thi Phuong Nam Bui (ORCID: https://orcid.org/0000-0001-5366-5960)
- Sjef Boeren
- Samuel Bellais
- Nathalie M. Delzenne (ORCID: https://orcid.org/0000-0003-2115-6082)
- Massimo Federici (ORCID: https://orcid.org/0000-0003-4989-5194)
- Rémy Burcelin (ORCID: https://orcid.org/0000-0002-7942-8346)
- Matthias Van Hul (ORCID: https://orcid.org/0000-0002-5503-107X)
- Anthony Puel
- Giulio G. Muccioli (ORCID: https://orcid.org/0000-0002-1600-9259)
- Tiphaine Le Roy (ORCID: https://orcid.org/0000-0002-0874-1490)
- Lesley Hoyles (ORCID: https://orcid.org/0000-0002-6418-342X)
- Giselle C. Wong (ORCID: https://orcid.org/0000-0003-3084-0599)
- Mélanie Nehlich
- Patrice D. Cani (ORCID: https://orcid.org/0000-0003-2040-2448)
- Camille Petitfils (ORCID: https://orcid.org/0000-0002-6884-300X)
- Thomas Clavel (ORCID: https://orcid.org/0000-0002-7229-5595)
- Andrea Scaloni (ORCID: https://orcid.org/0000-0001-9362-8515)
- Manyi Jia (ORCID: https://orcid.org/0000-0001-9467-1494)
- José Manuel Fernandez-Real
- Dumas Marc-Emmanuel
- Bouthaina Ben Abdallah
- Chi-Hsien Lee
- Thomas Leicht
- Ching Jian
- Willem M De Vos
Institutions
- University of Rome Tor Vergata (IT)
- Centre National de la Recherche Scientifique (FR)
- University of Helsinki (FI)
- Inserm (FR)
- Universitat de Girona (ES)
- Instituto de Salud Carlos III (ES)
- Istituto Neurologico Mediterraneo (IT)
- Sorbonne Université (FR)
- Nutrition et obésité : approches systémiques (FR)
- Istituto per il Sistema Produzione Animale in Ambiente Mediterraneo (IT)
- Centro de Investigación Biomédica en Red (ES)
- Hôpital Rangueil (FR)
- BIOASTER (FR)
- Walloon Excellence in Lifesciences and Biotechnology (BE)
- Amsterdam University Medical Centers (NL)
- Hospital Universitari de Girona Doctor Josep Trueta (ES)
- National Research Council (IT)
- European Genomic Institute for Diabetes (FR)
- Imperial College London (GB)
- Nottingham Trent University (GB)
- University of Amsterdam (NL)
- RWTH Aachen University (DE)
- Wageningen University & Research (NL)
- UCLouvain (BE)
Publication Details
- Journal
- Gut
- Published
- 2026-01-07
- DOI
- https://doi.org/10.1136/gutjnl-2025-336617
- Citations
- 1
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 31.52