ASSESSMENT OF DRUG UTILIZATION PATTERN AND QUALITY OF LIFE USING MODIFIED DIABETES QUALITY OF LIFE (MDQoL)-17 QUESTIONNAIRE

Introduction: Type II Diabetes Mellitus is a chronic metabolic disease characterized by insulin resistance and impaired insulin secretion. The wide range of antidiabetic medications and patient-specific factors contribute to diverse drug utilization patterns. Understanding these patterns is crucial for identifying potential issues such as irrational drug use, polypharmacy, and non-adherence. Objectives: To evaluate drug utilization patterns in Type II DM patients and determine quality of life using the Modified Diabetes Quality of Life (MDQoL-17) questionnaire. Materials and Methods: An observational cross-sectional study was conducted at Shridevi Institute of Medical Sciences and Research Hospital, Tumakuru, involving 100 Type II DM patients. Patients were included in the study only after obtaining written informed consent form; all relevant data were collected from case record forms and were analysed to assess the drug utilization while Health-related quality of life was assessed using MDQoL-17. Data was analyzed using JAMOVI version 2.6.44. Results: Most participants were aged 51-60 years (35%) with mean age 56.7±11.9 years; 52% were males. Hypertension (52%) was the most common comorbidity. Glimepiride Metformin was the most prescribed regimen. Mean MDQoL-17 scores showed lowest values in general health perception (40.00±19.71) and energy/fatigue (51.00±28.48). Higher HbA1C significantly correlated with lower QoL (p<0.05). Conclusion: Glimepiride+Metformin was most commonly prescribed, reflecting rational therapy. Quality of life was moderately affected, mainly in general health and energy domains. Effective glycaemic control and holistic management are essential to improve overall well-being. Word Count: 248 words.