Outcomes of Oral Antidiabetic Drugs in Metabolic Dysfunction-Associated Steatotic Liver Disease: A Nationwide Target Trial Emulation Study

In patients with concurrent T2DM and MASLD, SGLT2 inhibitors demonstrated better cardiovascular outcomes compared to other OADs. These findings suggest that SGLT2 inhibitors may be the preferred OAD choice for cardiovascular risk reduction in this high-risk population.

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Publication Details

Journal
Clinical and Molecular Hepatology
Published
2026-01-06
DOI
https://doi.org/10.3350/cmh.2025.1006
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Outcomes of Oral Antidiabetic Drugs in Metabolic Dysfunction-Associated Steatotic Liver Disease: A Nationwide Target Trial Emulation Study

Yeonjin Kim, Bokyung Koo, S Romeo, Sae Kyung Joo et al.
Clinical and Molecular Hepatology
Liver Disease Diagnosis and Treatment
article

Outcomes of Oral Antidiabetic Drugs in Metabolic Dysfunction-Associated Steatotic Liver Disease: A Nationwide Target Trial Emulation Study

Yeonjin Kim, Bokyung Koo, S Romeo, Sae Kyung Joo, W. Lee, Heejoon Jang, Dong Hyeon Lee, Yoo Kyoung Lim, Won Kim
article en

Abstract

In patients with concurrent T2DM and MASLD, SGLT2 inhibitors demonstrated better cardiovascular outcomes compared to other OADs. These findings suggest that SGLT2 inhibitors may be the preferred OAD choice for cardiovascular risk reduction in this high-risk population.

Clinical and Molecular Hepatology
Seoul National University (KR), Seoul Metropolitan Government (KR), Karolinska Institutet (SE), SNUH SMG-SNU Boramae Medical Center (KR)
National Research Foundation, Korean Association for the Study of the Liver
Good health and well-being
Openalex Percentile: Top 95%
Liver Disease Diagnosis and Treatment
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